Conference Program

26 September 2016 - Monday

15:00-18:25

Registration

16:00-17:25

Meeting of International Advisory, Scientific and Director Board of the Research Center for Molecular Mechanisms of Aging and Age-Related Diseases.

17:30-18:30

Satellite event: Open lecture by Marat Yusupov “Ribosome a Largest Molecular Machinery of the Cell”

18:35-19:35

Satellite event: Open lecture by Valery Fokin “Selective Nicotinic Acetylcholine Receptors Agonists for Cognitive Improvement”


27 September 2016 - Tuesday

08:00-08:55

Registration

09:00-09:30

Opening of the conference. Welcome address from MIPT rectorate, Board of the Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Conference committees.

09:30-10:15

Keynote lecture: Werner Kühlbrandt “Cryo Electron Microscopy with Mitochondrial Membrane Complexes”

10:20-11:05

Keynote lecture: Antti Niemi “Folding Proteins at the Speed of Life”

11:05-11:35

Coffee Break and Poster Session

11:35-12:20

Keynote lecture: Vladimir Anisimov “Longevity: Free Choice of Destiny”

12:25-12:55

Christoph Fahlke “Glutamate Transporter Dysfunction in Human Diseases”

13:00-13:25

Olga Sokolova “Conformational States Underlying Autoregulation of F-BAR Domain Membrane Remodelling”

13:25-14:50

Lunch

14:50-15:20

Max Maletta “Cryo Electron Microscopy and the FEI Volta Phase Plate as Tools for Studying Biomembranes”

15:25-15:55

Michiru D. Sugawa “Shaping Strategies in Healthy Longevity Science”

16:00-16:45

Keynote lecture: Isao Shimokawa “Anti-Ageing Effect of Dietary Restriction”

16:50-17:20

Andrei Gilep “Steroidogenic Cytochrome P450s: Protein-Membrane and Protein-Protein Interactions”

17:25-17:30

Andrey Rogachev, Information from the Organizing Committee

17:30-18:00

Coffee Break and Poster Session

18:00-19:00

Satellite event: Open lecture by Antti Niemi “What is Life - a Physics Point of View”

19:05-20:05

Satellite event: Open lecture by Isao Shimokawa “Experimental interventions for longevity”


28 September 2016 - Wednesday

09:00-09:10

Information from Organizing and Program Committees

09:10-09:40

Sergei Grudinin “Using Machine-Learning, Artificial Intelligence and Integrative Approaches for Protein Structure Predictions”

09:45-10:15

Alexander Myasnikov "High Resolution Electron Microscopy in Protein Synthesis Investigation"

10:20-10:50

Francisco Rodriguez-Valera “Metagenomics of Aquatic Microbes, a Window into the Diversity of Rhodopsins”

10:50-11:20

Coffee Break and Poster Session

11:20-11:50

Boris Gorshunov “Dielectric Spectroscopy of Biological Materials”

11:55-12:40

Keynote lecture: Raymond Stevens “GPCRs and Diseases”

12:45-13:15

Raul Gainetdinov “Emerging Pharmacology of Trace-Amine Associated Receptors (TAARs)”

13:15-14:40

Lunch

14:40-15:10

Vernon Smith “Pushing Back Frontiers: In-house GPCR Crystallography in
Structure-based Drug Design”

15:15-15:45

Martin Engelhard “Two-Component Signaling System”

15:50-16:35

Keynote lecture: Norbert Dencher “Mitochondrial Membranes as the Site of Ageing and of Neurodegenerative Diseases”

16:40-17:10

Vadim Cherezov “G-Protein Coupled Receptors and Ageing”

17:10-17:50

Coffee Break and Workshop from Helicon Company & Thermo Fisher Scientific: "Multiparameter Cell Analysis: from Individual Cells to Phenotypic Profiling".

17:50-18:20

Elena Vorontsova "Rapid Analysis of Fluorescence Microscopy Images"

18:25-19:10

Keynote lecture: Marat Yusupov ”Structural Studies of the Mechanism of Translation”

19:15-19:40

Eduard Bocharov “«Hot Spots» for Pathogenic Gain-of-Function Mutations in RTK Transmembrane Domains”

19:45-20:10

Olga Bocharova “Structural Insights into Initial Steps of Alzheimer Disease Development via Conformational Variability of APP Transmembrane Domain”

29 September 2016 - Thursday

09:00-09:10

Information from Organizing and Program Committees

09:10-09:40

Alexei Nikulin “Regulatory RNA in Bacteria and Archaea: Their Interaction with Sm-like (LSm) Proteins”

09:45-10:30

Keynote lecture: Dietmar Manstein “New Concepts for the Treatment of Myopathies”

10:35-11:05

James Liu “Structural and Functional Study of Human GPCRs”

11:10-11:40

Oxana Galzitskaya “The Mechanism Underlying Amyloid Polymorphism is Opened for Alzheimer Aβ Peptide”

11:40-12:10

Coffee Break and Poster Session

12:10-12:40

Sergei Kozin “Aged Isoform of β-amyloid as Biomarker and Drug Target of Alzheimer’s Disease”

12:45-13:10

Plamena Stroh “Mechanism of Neurodegeneration in Parkinson’s Disease”

13:15-13:45

Thomas Gensch “Determination of Intracellular Ion Concentrations by Fluorescence Life-Time Imaging”

13:50-14:15

Konstantin Mineev “Role of Membrane Domains and Juxtamembrane Regions in p75 Neurotrophin Signaling”

14:20-14:50

Ravinder Anand-Ivell “Relaxin Family Members and Their GPCRs as Modulators of Health and Aging”

14:50-15:50

Lunch

17:15-18:45

Social event: excursion to The Tretyakov Gallery


30 September 2016 - Friday

09:00-09:10

Information from Organizing and Program Committees

09:10-09:40

Judith Haendeler “Molecules Relevant for Vascular Aging – Specific Role in Mitochondrial p27”

09:45-10:15

Joachim Altschmied “Role of Mitochondrial Telomerase Reverse Transcriptase in the Cardiovascular System”

10:20-11:05

Keynote lecture: Ernst Bamberg ”Optogenetics: Basics, Applications and New Developments”

11:10-11:55

Keynote lecture: Georg Büldt “Retinal proteins inspired biophysical studies”

11:55-12:30

Coffee Break and Poster Session

12:30-13:00

Igor Chizhov “Kinetics and Energetics of Ion Transport in Retinal Proteins

13:05-13:35

Roman Efremov “Biomembranes: Results of Computer Studies”

13:40-14:05

Michael Proskurin/Alla Karpova “FlinChR: a New Optogenetic Tool and Its Application for Neural Circuit Dissection”

14:10-14:35

Anton Chugunov “Unique Structural Organization of Prokaryotic Membranes Probed by High-Performance Computing”

14:35-14:45

Closing the Conference

14:45-16:00

Lunch

Satellite event: Round Table “Development of Research Center for Molecular Mechanisms of Aging and Age-Related Diseases” at MIPT

16:00-16:20

Valentin Gordeliy, Major results of 2014-2016 and future plans

16:25-16:35

Valentin Borshchevskiy “A New Story of Old Bacteriorhodopsin”

16:40-16:55

Vitaliy Shevchenko “Would You Believe That Such Rhodopsin May Exist?”

17:00-17:10

Ivan Gushchin “Crystallographic Studies of Membrane Proteins”

17:15-17:25

Alexandra Luginina “Towards a New GPCR Structure”

17:25-18:00

Coffee Break

18:00-19:00

Tagir Aushev “MIPT View of the Future Center of Aging”

17:50-18:50

Closing Discussions